At least 90 people were wounded in the clashes, the Palestinian Red Crescent said, with around 15 people seriously hurt by rubber-coated steel bullets, teargas inhalation and at the hands of Israeli police.
Israel security forces said about eight police officers were lightly injured in clashes that ended with up to 60 arrests.
About 3,000 police officers had been deployed in East Jerusalem and nearby villages after Hamas and other Palestinian groups called for action in response to the reopening of the Hurva synagogue.
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